Single Animal or Combined Litter Sample

1 - 4 days

Diarrhea RealPCR™ Panel (Comprehensive)—Feline

3 - 5 g (1 g minimum) fresh feces in a sterile container, RTFC (Red Top Fecal Container) preferred; keep refrigerated.

Fresh Feces up to 10 days at 36° to 46° F (2° to 8° C), keep refrigerated.

• C. Perfringens Alpha Toxin (CPA)
• C. Perfringens Enterotoxin (CPE)
• Campylobacter Coli
• Campylobacter Jejuni
• Cryptosporidium Spp.
• Feline Coronavirus (FeCoV)
• Feline Panleukopenia Virus (FPV)
• Giardia Spp.
• Salmonella Spp.
• Toxoplasma Gondii
• Tritrichomonas Blagburni

Result indicates that the nucleic acid (DNA or RNA) of that organism(s) was not detected in the sample submitted. However, a negative PCR result may be caused by the number of organisms being below the limit of detection, decreased numbers of organisms following treatment or chronic carrier state, or the occurrence of a new strain variation.

Result indicates that the nucleic acid (DNA or RNA) of that organism(s) was detected in the fecal sample. In a patient with diarrhea, this supports infection. Vaccination with a modified live coronavirus vaccine may result in a positive result for up to a few weeks post-vaccination. Clostridium perfringens toxin genes (CPA and CPE) positive PCR results should be interpreted based on their quantitative levels. Note that recent or concurrent antibiotic against Clostridium will lower the quantitative levels. In animals with CPA or CPE gene copies > 300 Thous/g feces, the toxin may be contributing to clinical signs of diarrhea. In animals where the number of copies of the gene is below the cut-off, this toxin is unlikely to be contributing to diarrhea.

Includes quantification of Clostridium Perfringens Alpha Toxin (CPA) and Clostridium Perfringens Enterotoxin (CPE) genes if PCR positive.

[PCR] poor sample quality / aged sample / recent vaccination with modified live vaccines / recent antimicrobial or antiviral therapy.

The coronavirus test included in this panel is specific to feline enteric coronavirus and does not detect SARS-CoV-2, the causative agent in COVID-19. Feline enteric coronavirus is species-specific and does not infect humans.

Single Animal or Combined Litter Sample

RealPCR / Immunoassays

1 - 4 days

Diarrhea RealPCR™ Panel (Comprehensive)—Feline / Fecal Dx® Profile

Submit separate specimens for RealPCR and DX Profile. Two containers each containing: 3 – 5 g (1 g minimum) fresh feces in a sterile container, RTFC (Red Top Fecal Container) preferred; keep refrigerated.

Fresh Feces up to 10 days at 36° to 46° F (2° to 8° C), keep refrigerated.

• C. Perfringens Alpha Toxin (CPA)
• C. Perfringens Enterotoxin (CPE)
• Campylobacter Coli
• Campylobacter Jejuni
• Cryptosporidium Spp.
• Fecal Ova and Parasites
• Feline Coronavirus (FeCoV)
• Feline Panleukopenia Virus (FPV)
• Flea Tapeworm Antigen
• Giardia Spp.
• Hookworm Antigen
• Roundworm Antigen
• Salmonella Spp.
• Toxoplasma Gondii
• Tritrichomonas Blagburni
• Whipworm Antigen

Result indicates that the nucleic acid (DNA or RNA) of that organism(s) was not detected in the sample submitted. However, a negative PCR result may be caused by the number of organisms being below the limit of detection, decreased numbers of organisms following treatment or chronic carrier state, or the occurrence of a new strain variation.

Result indicates that the nucleic acid (DNA or RNA) of that organism(s) was detected in the fecal sample. In a patient with diarrhea, this supports infection. Vaccination with a modified live coronavirus vaccine may result in a positive result for up to a few weeks post-vaccination. Clostridium perfringens toxin genes (CPA and CPE) positive PCR results should be interpreted based on their quantitative levels. Note that recent or concurrent antibiotic against Clostridium will lower the quantitative levels. In animals with CPA or CPE gene copies > 300 Thous/g feces, the toxin may be contributing to clinical signs of diarrhea. In animals where the number of copies of the gene is below the cut-off, this toxin is unlikely to be contributing to diarrhea.

Includes quantification of Clostridium Perfringens Alpha Toxin (CPA) and Clostridium Perfringens Enterotoxin (CPE) genes if PCR positive.

[PCR] poor sample quality / aged sample / recent vaccination with modified live vaccines / recent antimicrobial or antiviral therapy. [Fecal O&P] poor sample quality / aged sample / small sample / freezing / non-formalin fixatives / samples contacting ground for >= 30 minutes.

The coronavirus test included in this panel is specific to feline enteric coronavirus and does not detect SARS-CoV-2, the causative agent in COVID-19. Feline enteric coronavirus is species-specific and does not infect humans.

Single Animal or Combined Litter Sample

1 - 4 day

Coccidioides spp. RealPCR™ Test

3 – 5 g (1 g minimum) fresh feces in a sterile container, RTFC (Red Top Fecal Container) preferred; keep refrigerated.

Fresh Feces up to 10 days at 36° to 46° F (2° to 8° C), keep refrigerated.

• Coccidioides Spp.

Result indicates that Coccidioides DNA was not detected in the sample submitted and other causes of clinical disease should be investigated. However, a negative PCR result may be caused by the numbers of organisms being below the limit of detection, decreased numbers of organisms following treatment or chronic carrier state, or the occurrence of new strain variations.

Result indicates that Coccidioides DNA was detected in the sample submitted. In animals with clinical signs, this supports infection. Dry or productive cough with concurrent fever, partial anorexia and weight loss is the most common clinical manifestation of disease. More severe respiratory signs may occur. With disseminated disease, lameness, localized peripheral lymphadenopathy, draining skin lesions, keratitis, uveitis, acute blindness, seizures, ataxia, behavioral changes, and coma can occur.

Common Name: Valley Fever

[PCR] poor sample quality / aged sample / recent vaccination with modified live vaccines / recent antimicrobial or antiviral therapy.

Single Animal or Combined Litter Sample

1 day

Fecal Dx® Profile with Giardia

3 – 5 g (1 g minimum) fresh feces in a sterile container, RTFC (Red Top Fecal Container) preferred; keep refrigerated.

Fresh Feces up to 10 days at 36° to 46° F (2° to 8° C), keep refrigerated.

• Fecal Ova and Parasites
• Flea Tapeworm Antigen
• Giardia Antigen
• Hookworm Antigen
• Roundworm Antigen
• Whipworm Antigen

[Fecal O&P] poor sample quality / aged sample / small sample / freezing / non-formalin fixatives / samples contacting ground for >= 30 minutes. [Giardia] poor sample quality / aged sample / improper storage / PVA fixative / SAF.

1 - 4 days; allow additional time for strain identification if influenza A virus PCR positive

Upper Respiratory Disease (URD) RealPCR™ Panel—Feline

Deep pharyngeal swab (with visible organic material on swab; please rub firmly) and a conjunctival swab (wipe eye clean, swab inside of eyelid) in the same tube. Please submit dry, plastic-stemmed swabs, without transport media, in a WTT (White Top Tube); keep refrigerated.

Pharyngeal and Conjunctival Swab up to 10 days at 36° to 46° F (2° to 8° C), keep refrigerated.

• Bordetella Bronchiseptica
• Chlamydophila Felis (C. felis)
• Feline Calicivirus (FCV)
• Feline Herpesvirus Type 1 (FHV-1)
• Influenza Virus (H7N2)
• Influenza A Virus (H1N1)
• Influenza A Virus (H3N2)
• Influenza A Virus (H3N8)
• Influenza A Virus (H7N2)
• Mycoplasma Felis (Mhf)

Result supports the absence of an infectious cause by these organisms for the clinical signs. PCR may not detect 100% of the isolates for the tested pathogens in a chronic carrier state, or the occurrence of a new strain variation.

Result indicates the detected organism(s) is likely an infectious cause for the clinical signs. Additional causes for the clinical signs should be assessed separately. Vaccination with a modified live vaccine may result in positive results for up to a few weeks post-vaccination.

Includes quantification of feline herpesvirus type 1 (FHV-1) viral particles if PCR positive. Includes strain identification for influenza A virus if PCR positive.

[PCR] poor sample quality / aged sample / recent vaccination with modified live vaccines / recent antimicrobial or antiviral therapy.

1 - 4 days

Ringworm (Dermatophyte) RealPCR™ Panel

Plucked hair with follicles (minimum 10 – 20 visible hairs) and skin scrapings from the active border of lesion (preferred) in WTT (White Top Tube), if no distinct lesions are present, pluck hairs from site of prior lesions (if known) and/or submit hair from a thorough coat brushing, using a toothbrush in WTT (White Top Tube); keep refrigerated.

Hair and Skin Scrapings up to 10 days at 36° to 46° F (2° to 8° C), keep refrigerated.

• Microsporum Canis
• Microsporum Spp.
• Trichophyton Spp.

Result indicates that DNA of Microsporum spp or Trichophyton spp organism(s) was not detected in the sample submitted. However, a negative PCR result may be caused by the numbers of organisms being below the limit of detection, decreased numbers of organisms following treatment or chronic, carrier state, or the occurrence of a new strain variation.

Result indicates that DNA of Microsporum spp. or Trichophyton spp. was detected in the submitted sample. In a patient with clinical signs, this supports infection. Positive resuls may also be seen in nonclinical patients in a carrier state. Zoonotic potential exist.

[PCR] poor sample quality / aged sample / recent vaccination with modified live vaccines / recent antimicrobial or antiviral therapy.

RealPCR / Microbiology

1 - 4 days; allow 14–16 days for the fungal culture

Ringworm (Dermatophyte) RealPCR™ Panel / Fungal Culture (on selective dermatophyte media)

Submit separate specimens for RealPCR and Fungal Culture. Two containers each containing: Plucked hair with follicles (minimum 10 – 20 visible hairs) and skin scrapings from the active border of lesion (preferred) in WTT (White Top Tube), if no distinct lesions are present, pluck hairs from site of prior lesions (if known) and/or submit hair from a thorough coat brushing, using a toothbrush in WTT (White Top Tube); keep refrigerated.

Hair and Skin Scrapings up to 10 days at 36° to 46° F (2° to 8° C), keep refrigerated.

• Microsporum Canis
• Microsporum Spp.
• Trichophyton Spp.

• Fungal Culture (on selective dermatophyte media)

Result indicates that DNA of Microsporum spp or Trichophyton spp organism(s) was not detected in the sample submitted. However, a negative PCR result may be caused by the numbers of organisms being below the limit of detection, decreased numbers of organisms following treatment or chronic, carrier state, or the occurrence of a new strain variation.

Result indicates that DNA of Microsporum spp. or Trichophyton spp. was detected in the submitted sample. In a patient with clinical signs, this supports infection. Positive resuls may also be seen in nonclinical patients in a carrier state. Zoonotic potential exist.

Fungal culture will only be performed if a separate specimen is submitted for culture.

[PCR] poor sample quality / aged sample / recent vaccination with modified live vaccines / recent antimicrobial or antiviral therapy. [Culture] poor sample quality / aged sample / recent antimicrobial or antiviral therapy / anticoagulants / formalin.

This test may only be ordered by breeders for intact studs, as its results are not applicable to pet parents of neutered males.

Hematology & Coagulation

1 - 3 days

Semen Analysis

1 mL semen in a sterile container, WTT (White Top Tube) preferred; keep at room temperature.

Semen up to 3 days at 59° to 77° F (15° to 22° C), keep at room temperature.

• Pathologist Report
• Semen Appearance
• Sperm/mL
• Volume Received

Semen for examination can be obtained by inserting a moistened cotton swab (Puritan PCR Swab) into the vulva of a queen immediately after mating, or the cat can be electro-ejaculated under general anesthesia. These are the most common methods in felids and enable one to obtain ejaculates of reasonably good quality.

[Semen] poor sample quality / aged sample / small sample / exposure to temperature extremes / semen extender.

This test may only be ordered by breeders for intact queens, as its results are not applicable to pet parents of spayed females.

1-4 days

Streptococcus Abortion RealPCR™ Panel

Vaginal swab (with visible organic material on swab; please rub firmly) in WTT (White Top Tube) and fresh placental tissue (if available) in a sterile container, RTFC (Red Top Fecal Container) preferred; keep refrigerated.

Vaginal Swab up to 72 hours at 36° to 46° F (2° to 8° C), keep refrigerated. Fresh tissue up to 24 hours at 36° to 46° F (2° to 8° C), keep refrigerated.

• Streptococcus Canis
• S. Dysgalactiae Equisimilis
• S. Equi Zooepidemicus

Result indicates that beta hemolytic Streptococci DNA was not detected in the sample submitted. However, a negative PCR result may be caused by the numbers of organisms being below the limit of detection, decreased numbers of organisms following treatment or chronic carrier state, or the occurrence of a new strain variation.

Result indicates that DNA from this beta hemolytic Streptococci was detected in the sample submitted. In a patient with clinical signs and histopathology findings, this supports infection. Certain chronic infections may not be the primary cause for the reproductive problems and additional causes should be assessed separately.

It is preferred to have fresh placental tissue for testing, but the panel can be run solely on the vaginal swabs with the understanding that the levels of infection may not be as pronounced as inside the placenta.

[PCR] poor sample quality / aged sample / recent vaccination with modified live vaccines / recent antimicrobial or antiviral therapy.

Gas Chromatography Mass Spectrometry (GC-MS)

15 - 23 days

This is an extensive screen for a wide variety of pesticides, drugs, pollutants, and industrial chemicals.

10 mL urine divided into two sterile container, WTT (White Top Tube) preferred; keep refrigerated. Please specify collection method. Optionally: 100 g rumen/crop/stomach contents in a sterile container, RTFC (Red Top Fecal Container) preferred; keep refrigerated. This test can also be run on the suspected material: 400 g in a sterile container, RTFC (Red Top Fecal Container) preferred; keep refrigerated.

Urine up to 24 hours at 36° to 46° F (2° to 8° C), keep refrigerated. Stomach Contents up to 24 hours at 36° to 46° F (2° to 8° C), keep refrigerated.

• Toxicology Urine Screening

Submission of the most appropriate sample type, based on clinical history and toxins suspected, is important for best results. If there is uncertainty about which sample type to submit, consultation with a clinical toxicologist is recommended.

[Mass-Spec] poor sample quality / aged sample / exposure to temperature extremes / formalin / saline.

8:00am for Urinalysis

Urinalysis: physical, chemical and microscopic analyses

5 mL urine in a sterile container, WTT (White Top Tube) preferred; keep refrigerated. Please specify collection method.

Urine up to 24 hours at 36° to 46° F (2° to 8° C), keep refrigerated.

• Bacteria
• Bilirubin
• Blood
• Casts
• Clarity
• Color
• Crystals
• Cystatin B
• Epi Cell
• Glucose
• Ketones
• Mucus
• Ph
• Protein
• RBC
• Specific Gravity
• Urobilinogen
• WBC

Do not submit syringes with needles.

[Urinalysis] poor sample quality / aged sample / clot activator / EDTA / myoglobinuria or hemoglobinuria may cause a positive for blood on dipstick in the absence of red blood cells on sediment / captopril and ace-inhibitors may cause false negative for blood on dipstick.

2-5 days if culture positive, with negative results reported in 1-2 days

Urine Culture (ID with MIC Susceptibility)

5 mL urine in a sterile container, WTT (White Top Tube) preferred; keep refrigerated. Please specify collection method.

Urine up to 24 hours at 36° to 46° F (2° to 8° C), keep refrigerated.

• Urine Culture

Results reported as no growth, or identification and susceptibility (aerobic only). Most, but not all cultures, will also include minimum inhibitory concentrations (MIC) with the susceptibility. IDEXX follows the guidelines set by the Clinical and Laboratory Standards Institute (CLSI), formerly the National Committee for Clinical Laboratory Standards (NCCLS), combined with our years of experience in performing susceptibility testing. Susceptibilities will not be performed on normal flora or nonpathogenic organisms. Pathogens with predictable susceptibility patterns, or with no CLSI interpretive standards will be reported with a recommended list of antimicrobials. Examples include β-hemolytic streptococci (beta-strep) and Pasteurella in nonsterile sites. Pathogens that are not suitable for routine susceptibility testing, due to their growth characteristics (i.e. slow-growing, anaerobic) or lack standardized methodology for testing, will be reported with recommended antibiotics. Examples include Corynebacterium pseudotuberculosis and Actinomyces spp.

Do not submit syringes with needles.

[Culture] poor sample quality / aged sample / recent antimicrobial or antiviral therapy / anticoagulants / formalin.

Chemistry & Culture

8:00am for Urinalysis. 2-5 days if culture positive, with negative results reported in 1-2 days

Urinalysis: physical, chemical and microscopic analyses / Urine Culture (ID with MIC Susceptibility)

10 mL urine divided into two sterile container, WTT (White Top Tube) preferred; keep refrigerated. Please specify collection method.

24 hours at 36° to 46° F (2° to 8° C), keep refrigerated.

• Bacteria
• Bilirubin
• Blood
• Casts
• Clarity
• Color
• Crystals
• Cystatin B
• Epi Cell
• Glucose
• Ketones
• Mucus
• Ph
• Protein
• RBC
• Specific Gravity
• Urobilinogen
• WBC

• Urine Culture

Results reported as no growth, or identification and susceptibility (aerobic only). Most, but not all cultures, will also include minimum inhibitory concentrations (MIC) with the susceptibility. IDEXX follows the guidelines set by the Clinical and Laboratory Standards Institute (CLSI), formerly the National Committee for Clinical Laboratory Standards (NCCLS), combined with our years of experience in performing susceptibility testing. Susceptibilities will not be performed on normal flora or nonpathogenic organisms. Pathogens with predictable susceptibility patterns, or with no CLSI interpretive standards will be reported with a recommended list of antimicrobials. Examples include β-hemolytic streptococci (beta-strep) and Pasteurella in nonsterile sites. Pathogens that are not suitable for routine susceptibility testing, due to their growth characteristics (i.e. slow-growing, anaerobic) or lack standardized methodology for testing, will be reported with recommended antibiotics. Examples include Corynebacterium pseudotuberculosis and Actinomyces spp.

Do not submit syringes with needles.

[Urinalysis] poor sample quality / aged sample / clot activator / EDTA / myoglobinuria or hemoglobinuria may cause a positive for blood on dipstick in the absence of red blood cells on sediment / captopril and ace-inhibitors may cause false negative for blood on dipstick. [Culture] poor sample quality / aged sample / recent antimicrobial or antiviral therapy / anticoagulants / formalin.

RealPCR / Immunoassays

1 - 4 days; allow additional time for strain identification if influenza A virus PCR positive

Upper Respiratory Disease (URD) RealPCR™ Panel—Feline / Diarrhea RealPCR™ Panel (Comprehensive)—Feline / Fecal Dx® Profile

Deep pharyngeal swab (with visible organic material on swab; please rub firmly) and a conjunctival swab (wipe eye clean, swab inside of eyelid) in the same tube. Please submit dry, plastic-stemmed swabs, without transport media, in a WTT (White Top Tube); keep refrigerated.

Submit separate specimens for RealPCR and DX Profile. Two containers each containing: 3 – 5 g (1 g minimum) fresh feces in a sterile container, RTFC (Red Top Fecal Container) preferred; keep refrigerated.

Pharyngeal and Conjunctival Swab up to 10 days at 36° to 46° F (2° to 8° C), keep refrigerated. Fresh Feces up to 10 days at 36° to 46° F (2° to 8° C), keep refrigerated.

• Bordetella Bronchiseptica
• C. Perfringens Alpha Toxin (CPA)
• C. Perfringens Enterotoxin (CPE)
• Campylobacter Coli
• Campylobacter Jejuni
• Chlamydophila Felis (C. felis)
• Cryptosporidium Spp.
• Fecal Ova and Parasites
• Feline Calicivirus (FCV)
• Feline Coronavirus (FeCoV)
• Feline Herpesvirus Type 1 (FHV-1)
• Feline Panleukopenia Virus (FPV)
• Flea Tapeworm Antigen
• Giardia Spp.
• Hookworm Antigen
• Influenza Virus (H7N2)
• Influenza A Virus (H1N1)
• Influenza A Virus (H3N2)
• Influenza A Virus (H3N8)
• Influenza A Virus (H7N2)
• Mycoplasma Felis (Mhf)
• Roundworm Antigen
• Salmonella Spp.
• Toxoplasma Gondii
• Tritrichomonas Blagburni
• Whipworm Antigen

[2512] Result supports the absence of an infectious cause by these organisms for the clinical signs. PCR may not detect 100% of the isolates for the tested pathogens in a chronic carrier state, or the occurrence of a new strain variation. [3882] Result indicates that the nucleic acid (DNA or RNA) of that organism(s) was not detected in the sample submitted. However, a negative PCR result may be caused by the number of organisms being below the limit of detection, decreased numbers of organisms following treatment or chronic carrier state, or the occurrence of a new strain variation.

[2512] Result indicates the detected organism(s) is likely an infectious cause for the clinical signs. Additional causes for the clinical signs should be assessed separately. Vaccination with a modified live vaccine may result in positive results for up to a few weeks post-vaccination. [3882] Result indicates that the nucleic acid (DNA or RNA) of that organism(s) was detected in the fecal sample. In a patient with diarrhea, this supports infection. Vaccination with a modified live coronavirus vaccine may result in a positive result for up to a few weeks post-vaccination. Clostridium perfringens toxin genes (CPA and CPE) positive PCR results should be interpreted based on their quantitative levels. Note that recent or concurrent antibiotic against Clostridium will lower the quantitative levels. In animals with CPA or CPE gene copies > 300 Thous/g feces, the toxin may be contributing to clinical signs of diarrhea. In animals where the number of copies of the gene is below the cut-off, this toxin is unlikely to be contributing to diarrhea.

Includes quantification of feline herpesvirus type 1 (FHV-1) viral particles if PCR positive. Includes strain identification for influenza A virus if PCR positive. Includes quantification of Clostridium Perfringens Alpha Toxin (CPA) and Clostridium Perfringens Enterotoxin (CPE) genes if PCR positive.

[PCR] poor sample quality / aged sample / recent vaccination with modified live vaccines / recent antimicrobial or antiviral therapy. [Fecal O&P] poor sample quality / aged sample / small sample / freezing / non-formalin fixatives / samples contacting ground for >= 30 minutes.

The coronavirus test included in this panel is specific to feline enteric coronavirus and does not detect SARS-CoV-2, the causative agent in COVID-19. Feline enteric coronavirus is species-specific and does not infect humans.